Synthetic polymers with anticoagulant activity
نویسندگان
چکیده
منابع مشابه
Anticoagulant activity of synthetic hirudin peptides.
Synthetic peptides based on the COOH-terminal 21 residues of hirudin were prepared in order to 1) evaluate the role of this segment in hirudin action toward thrombin, 2) define the shortest peptide derivative with anticoagulant activity, and 3) investigate the role of tyrosine sulfation in the peptides' inhibitory activities. A hirudin derivative of 20 amino acids, Hir45-64 (derived from residu...
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ژورنال
عنوان ژورنال: Journal of Polymer Science: Polymer Symposia
سال: 2007
ISSN: 0360-8905,1936-0959
DOI: 10.1002/polc.5070660131